Tesamorelin is a Growth Hormone-Releasing Hormone (GHRH) analog originally FDA-approved for reducing visceral fat in HIV-associated lipodystrophy.
In the performance and longevity world, it’s used for:
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Fat loss (especially belly/visceral fat)
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Improving sleep
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Enhancing recovery
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Increasing IGF-1
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Better skin, collagen, and overall anti-aging
Tesamorelin is considered one of the strongest fat-loss peptides, far more potent and consistent than CJC-1295, Ipamorelin, or sermorelin.
How It Works
Tesamorelin stimulates the pituitary gland to increase pulsatile growth hormone release through:
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GHRH receptor activation (very powerful)
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Increased GH amplitude & frequency
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Higher IGF-1 → accelerated fat loss and recovery
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Reduced visceral adipose tissue (VAT)
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Improved cellular repair
It mimics your body’s natural growth hormone rhythm instead of forcing GH like exogenous HGH.
How to Use It
Administration
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Subcutaneous injection, typically abdomen
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Best taken before bed, fasted 2–3 hours for maximum GH pulses
Typical Dosage
Standard dose:
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2 mg once daily
If using research vials (5 mg, 10 mg, 15 mg):
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Reconstitute accordingly
Frequency
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Daily
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Don’t skip days, it works cumulatively.
Cycle Length
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8–12 weeks minimum
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16–24 weeks ideal for visceral fat changes
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Can be used year-round because it does not shut down endogenous GH.
- “For Research Use Only – Not For Human Consumption”
Positive and Negative Side Effects
Positive Side Effects
Stimulates Growth Hormone Production: Tesamorelin promotes the natural release of growth hormone, which can enhance fat metabolism and overall health.
Fat Loss: Known for its effectiveness in reducing visceral fat, particularly in individuals with HIV-associated lipodystrophy.
Improved Metabolic Function: May positively impact metabolic health and insulin sensitivity.
Preservation of Lean Muscle Mass: Helps maintain muscle mass while promoting fat loss.
Negative Side Effects
Injection Site Reactions: Common side effects include redness, swelling, or irritation at the injection site.
Potential Hormonal Imbalance: Improper use or excessive dosage could lead to hormonal imbalances or side effects related to elevated growth hormone levels.
Cost and Availability: Tesamorelin can be expensive and may not be widely available outside of specific medical contexts.
Product Disclaimer
We always suggest to do your own research before making a decision on which formulas are best for you. Listening to others may put you in danger, and we always recommend for newcomers to make themselves informed of all the benefits, and side effects.
“For Research Use Only – Not For Human Consumption”






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