
GHK-Cu: The Regenerative Peptide for Skin, Hair, and Cellular Renewal
GHK-Cu, also known as Copper Peptide, is a naturally occurring complex of the tripeptide GHK (glycyl-L-histidyl-L-lysine) bonded with copper ions. Recognized for decades in regenerative medicine and cosmetics, GHK-Cu is valued for its role in skin repair, hair growth, and overall cellular rejuvenation.
What Is GHK-Cu?
GHK-Cu is found naturally in human plasma, saliva, and tissue. Its biological activity revolves around promoting wound healing, reducing inflammation, and stimulating collagen production. It’s often described as a “signal peptide,” triggering repair and regeneration responses throughout the body.
In addition to skin repair, GHK-Cu supports:
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Hair follicle growth and scalp health
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Reduction in wrinkles and skin sagging
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Enhanced recovery from injury or oxidative stress
How Does GHK-Cu Work?
Stimulates Collagen and Elastin Production
GHK-Cu activates fibroblasts, the cells responsible for producing structural proteins that keep skin firm and elastic.
Improves Cellular Communication
It binds copper ions that serve as essential cofactors for antioxidant enzymes like superoxide dismutase (SOD), reducing oxidative stress in tissues.
Enhances Wound Healing
GHK-Cu promotes angiogenesis (new blood vessel formation) and accelerates tissue regeneration.
Benefits of GHK-Cu
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Smoother, firmer, and more youthful-looking skin
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Stimulation of hair growth and scalp rejuvenation
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Reduced wrinkles, scars, and sun damage
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Faster tissue healing and recovery
Side Effects and Safety
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Mild temporary irritation with topical application
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Minor redness or itching at injection sites
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Safe for most adults; no systemic adverse effects reported
How to Use GHK-Cu
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Dosage (Injectable): 100–200 mcg subcutaneously, 3–5x per week
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Cycle Length: Continuous or in 6–12 week blocks
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Administration: Subcutaneous injection
GHK-Cu Regenerative Stack
Compound | Dose | Frequency | Purpose |
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GHK-Cu | 200 mcg | 3–5x per week (SubQ) | Skin, hair, and collagen regeneration |
Epithalon | 10 mg | 2–3x per week (SubQ) | Cellular anti-aging and telomere support |
Collagen Peptides | 10–20 g | Daily (Oral) | Structural protein support |
Vitamin C | 500–1000 mg | Daily (Oral) | Collagen synthesis co-factor |
Notes: GHK-Cu performs best when supported with hydration, sleep, and nutrient-rich diets. When combined with Epithalon, it provides comprehensive rejuvenation from both a cellular and aesthetic standpoint.