GHK-Cu: The Regenerative Peptide for Skin, Hair, and Cellular Renewal

GHK-Cu, also known as Copper Peptide, is a naturally occurring complex of the tripeptide GHK (glycyl-L-histidyl-L-lysine) bonded with copper ions. Recognized for decades in regenerative medicine and cosmetics, GHK-Cu is valued for its role in skin repair, hair growth, and overall cellular rejuvenation.

What Is GHK-Cu?

GHK-Cu is found naturally in human plasma, saliva, and tissue. Its biological activity revolves around promoting wound healing, reducing inflammation, and stimulating collagen production. It’s often described as a “signal peptide,” triggering repair and regeneration responses throughout the body.

In addition to skin repair, GHK-Cu supports:

  • Hair follicle growth and scalp health

  • Reduction in wrinkles and skin sagging

  • Enhanced recovery from injury or oxidative stress

How Does GHK-Cu Work?

Stimulates Collagen and Elastin Production

GHK-Cu activates fibroblasts, the cells responsible for producing structural proteins that keep skin firm and elastic.

Improves Cellular Communication

It binds copper ions that serve as essential cofactors for antioxidant enzymes like superoxide dismutase (SOD), reducing oxidative stress in tissues.

Enhances Wound Healing

GHK-Cu promotes angiogenesis (new blood vessel formation) and accelerates tissue regeneration.

Benefits of GHK-Cu

  • Smoother, firmer, and more youthful-looking skin

  • Stimulation of hair growth and scalp rejuvenation

  • Reduced wrinkles, scars, and sun damage

  • Faster tissue healing and recovery

Side Effects and Safety

  • Mild temporary irritation with topical application

  • Minor redness or itching at injection sites

  • Safe for most adults; no systemic adverse effects reported

How to Use GHK-Cu

  • Dosage (Injectable): 100–200 mcg subcutaneously, 3–5x per week

  • Cycle Length: Continuous or in 6–12 week blocks

  • Administration: Subcutaneous injection

GHK-Cu Regenerative Stack

Compound Dose Frequency Purpose
GHK-Cu 200 mcg 3–5x per week (SubQ) Skin, hair, and collagen regeneration
Epithalon 10 mg 2–3x per week (SubQ) Cellular anti-aging and telomere support
Collagen Peptides 10–20 g Daily (Oral) Structural protein support
Vitamin C 500–1000 mg Daily (Oral) Collagen synthesis co-factor

Notes: GHK-Cu performs best when supported with hydration, sleep, and nutrient-rich diets. When combined with Epithalon, it provides comprehensive rejuvenation from both a cellular and aesthetic standpoint.

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