Name: KPV 10mg
SKU: PEP-0028
Availability: InStock

KPV 10mg

$75.00 – $700.00

KPV (Lysine–Proline–Valine) is a short anti-inflammatory tripeptide derived from the C-terminal end of alpha-melanocyte-stimulating hormone (α-MSH). While it does not have the pigmentation effects of α-MSH, it retains powerful anti-inflammatory, antimicrobial, and gut-protective properties. KPV is used for conditions involving systemic inflammation, gut dysfunction (like colitis or leaky gut), and autoimmune responses

How It Works

Blocks NF-κB Activation: KPV inhibits NF-κB, a key pro-inflammatory signaling molecule that drives inflammation and immune response.
Suppresses Cytokines: Reduces levels of inflammatory cytokines like TNF-α, IL-1β, and IL-6.
Supports Gut Barrier Integrity: Helps repair intestinal epithelium and tight junctions, beneficial in IBD, Crohn’s, or IBS.
Antimicrobial Action: Demonstrates direct effects against pathogens like Candida albicans and Staphylococcus aureus.
Immune Modulation: May help regulate overactive immune systems without broad immunosuppression.

How to Use KPV

Dosage:

200–500 mcg per day (subcutaneous)
Frequency: Once or twice daily depending on severity and delivery method
Cycle Length: 2–8 weeks depending on condition (may be used longer for chronic inflammation or gut healing)
Stacking: Commonly stacked with BPC-157, TB-500, or LL-37 for enhanced healing, or Melanotan II for added alpha-MSH benefits
Post-Cycle Consideration: None required; safe for ongoing therapeutic use
Administration: Subcutaneous (systemic), oral (gut), or topical (skin)

Positive and Negative Side Effects

Positive Side Effects

Powerful anti-inflammatory action
Supports gut healing and integrity
May help in autoimmune or inflammatory conditions
Can aid in skin conditions like psoriasis or eczema
Antimicrobial without contributing to antibiotic resistance
No known systemic side effects or hormone interaction

Negative Side Effects

Limited availability in some regions
Topical formulations may vary in strength and absorption
Injectable KPV may be less convenient for some users
Research is still emerging — most data from animal or early-phase human studies

Product Disclaimer

We always suggest to do your own research before making a decision on which formulas are best for you. Listening to others may put you in danger, and we always recommend for newcomers to make themselves informed of all the benefits, and side effects.