How It Works
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Mitochondrial Enhancement: Improves cellular energy by acting as an electron donor in the electron transport chain, bypassing dysfunctional mitochondria and restoring ATP production.
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Neuroprotection: Reduces brain inflammation and protects neurons from oxidative stress and degeneration.
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Antioxidant Effects: Acts as a potent reactive oxygen species (ROS) scavenger.
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Cognitive Boost: Increases memory, focus, and mood by modulating neurotransmitters like serotonin and dopamine.
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Antimicrobial & Antiviral: Shows broad-spectrum activity against bacteria, viruses, and fungi (though secondary in human use).
How to Use Methylene Blue
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Dosage:
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0.5 mg/kg to 4 mg/kg body weight orally is the most studied range.
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Nootropic dose: 5–20 mg/day is common for healthy users.
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Therapeutic protocols may use higher doses short term under medical supervision.
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Frequency:
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Daily or every other day, depending on dose and response.
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For cognitive or mitochondrial support, 5 days on / 2 off is popular.
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Cycle Length:
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4–8 weeks for cognitive benefits or mitochondrial support.
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Can be used long-term at low doses if well tolerated.
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Stacking:
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Often paired with NAD+, CoQ10, or Glutathione for mitochondrial synergy.
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Can enhance effects of nootropics like Alpha GPC, Lion’s Mane, or racetams.
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Caution when combined with SSRIs/MAOIs due to serotonin syndrome risk.
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Post-Cycle Consideration:
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None required. Tolerance is low at typical doses; some users rotate off every 1–2 months.
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Administration:
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Oral (liquid or capsules) is most common.
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Also available sublingually or IV in clinical settings (rare).
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Must be pharmaceutical grade—avoid aquarium-grade MB.
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Positive and Negative Side Effects
Positive Side Effects
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Increases mental clarity, memory, and motivation
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Supports mitochondrial health and ATP production
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Reduces brain fog and improves mood
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Enhances antioxidant defenses and resilience to stress
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May slow cognitive aging and neurodegeneration
Negative Side Effects
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Can stain urine, saliva, and teeth blue
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High doses may cause nausea, headache, or anxiety
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Risk of serotonin syndrome if combined with antidepressants (SSRIs, MAOIs, etc.)
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Can interfere with some blood or urine tests
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Not advised in individuals with G6PD deficiency
Product Disclaimer
We always suggest to do your own research before making a decision on which formulas are best for you. Listening to others may put you in danger, and we always recommend for newcomers to make themselves informed of all the benefits, and side effects.
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