Ipamorelin is a selective Growth Hormone Secretagogue (GHS) and one of the cleanest, safest GH-boosting peptides available. It stimulates natural growth hormone release without affecting cortisol or prolactin, making it a preferred choice for fat loss, muscle preservation, recovery, and overall anti-aging. Its gentle profile makes it a popular entry-level peptide.
How It Works
Ipamorelin binds to ghrelin receptors (GHS-R1a) in the pituitary and hypothalamus.
This triggers:
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Increased growth hormone (GH) release in small, natural pulses
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Stimulation of IGF-1 for tissue repair and fat loss
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Enhanced cellular regeneration
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Improved sleep quality, which amplifies fat burning and recovery
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No impact on cortisol, so it avoids stress-related side effects seen with older GHRPs like GHRP-6
Unlike CJC-1295 or Tesamorelin, Ipamorelin is mild but very well-tolerated.
How to Use It
Dosage:
Typical clinical study dose: 200–500 mcg per injection
Beginners often start at 200–300 mcg.
Frequency:
1–3 × daily depending on goals.
Best times:
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Morning fasted
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Pre-workout
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Before bed
Cycle Length:
8–12 weeks standard
Can be used long-term because it does not suppress endogenous GH.
Stacking:
Most common combos:
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CJC-1295 (no DAC) — synergistic GH pulses
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MOTS-c — metabolic support
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Tesamorelin — advanced fat-loss stack
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BPC-157 — recovery and healing support
Positive and Negative Side Effects
Positive Side Effects
Selective Action: Specifically targets GH release without significant impact on other hormones.
Muscle Enhancement: Promotes muscle growth and improves recovery times.
Fat Metabolism: Aids in fat loss, helping to improve body composition.
Anti-Aging Benefits: Potential improvements in skin quality, energy, and sleep.
Minimal Side Effects: Generally well-tolerated with fewer side effects compared to other GH
Negative Side Effects
Injection Site Reactions: Possible redness, swelling, or irritation at the injection site.
Hormonal Imbalance: Risk of hormonal imbalance if misused or dosed incorrectly.
Cost: Can be expensive and may not be easily accessible.
Variable Response: Individual responses can vary, and not everyone may experience the same benefits.
Product Disclaimer
We always suggest to do your own research before making a decision on which formulas are best for you. Listening to others may put you in danger, and we always recommend for newcomers to make themselves informed of all the benefits, and side effects.
“For Research Use Only – Not For Human Consumption”










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